Alzheimer Disorder:-

Definition:- 

Alzheimer’s disease (pronounced “alz-HAI-mirs”) is a brain condition that causes a progressive decline in memory, thinking, learning and organizing skills. It eventually affects a person’s ability to carry out basic daily activities. Alzheimer’s disease (AD) is the most common cause of dementia.

It is also called senile dementia.

Etiology:=

-Amyloid protein builds up in your brain cells, forming larger masses called plaques. Twisted fibers of another protein called tau form into tangles. These plaques and tangles block the communication between nerve cells, which prevents them from carrying out their processes.

The slow and ongoing death of the nerve cells results in the symptoms of Alzheimer’s disease. Nerve cell death starts in one area of your brain (usually in the area of your brain that controls memory — the hippocampus) and then spreads to other areas.

Symptoms:-Mild 

• Having difficulty finding the right words to express thoughts.
• Losing or misplacing objects more than usual.
• Having difficulty making plans or organizing.
• Having difficulty problem-solving.
• Taking longer to complete routine daily tasks.

Moderate stage symptoms:-

• Having difficulty finding the right words to express thoughts.
• Losing or misplacing objects more than usual.
• Having difficulty making plans or organizing.
• Having difficulty problem-solving.
• Taking longer to complete routine daily tasks.

Diagnosis:-

doctors conduct tests to assess memory impairment and other thinking skills, judge functional abilities, and identify behavior changes.

Treatment:-

• Cholinesterase inhibitors.
• NMDA antagonists.

The FDA has given accelerated approval for aducanub (Aduhelm™), the first disease-modifying therapy for Alzheimer’s disease. The medication helps to reduce amyloid deposits in your brain.